Ateliers Inserm 2024 - INSERM

Ateliers Inserm 2024

Atelier 279 - Phagothérapie : Concepts et Applications

Menu Télécharger : Programme

Mercredi 22 Mai 2024 - Wednesday, May 22, 2024

14:30 - 15:00 Reception of participants
15:00 - 15:15 Welcome and presentation by the organizers
15:15 - 16:00 Current needs and challenges of phage therapy: therapeutic failures, production, régulation, etc.
Fréderic LAURENT (Inserm U1111-HCL, Lyon, France)
SESSION I BIOLOGY OF BACTERIOPHAGES
16:00 - 16:45 Biology, taxonomy and genetics of phages
Laurent DEBARBIEUX (Institut Pasteur, Paris, France)
16:45 - 17:15 Coffee break
17:15 - 18:00 Diversity and mechanisms of bacterial resistance
François ROUSSET (Weizmann Institute of Science, Israël)
18:00 - 18:45 Phage experimental evolution
Rémy FROISSART (CNRS UMR 5290, Montpellier, France)
18:45 - 19:30 In vivo evaluations on animal models (host immune response / phage / bacteria)
Laurent DEBARBIEUX (Institut Pasteur, Paris, France)
19:30 Dinner

Jeudi 23 Mai 2024 - Thursday, May 23, 2024

06:30 - 08:30  Breakfast
SESSION II  THERAPEUTIC PHAGES: PREPARATIONS AND USE
08:30 - 09:30 Isolation, selection, bioproduction, purification, classical and innovative formulations and quality of therapeutic phages
Fabrice PIROT & Frédéric LAURENT (Hospices Civils de Lyon, France)
09:30 - 10:00 Phage Susceptibility Testing
Camille KOLENDA (Inserm U1111 - HCL, Lyon, France)
10:00 - 10:30 Coffee break
10:30 - 11:15 Phage therapy and PK/PD: interests and modelling
Gregory RESCH (Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse)
11:15 - 11:45 Association of bacteriophages and antibiotics and biofilms
Luis MELO (University of Minho, Portugal)
11:45 - 12:30 Phage engineering, Synthetic phages
Raphaël LAURENCEAU (Institut Pasteur, Paris, France)
12:30 - 14:00 Lunch
SESSION III REGULATORY FRAMEWORKS & EUROPEAN EXPERIENCES
14:00 - 14:30 Phages in society: Socio-technical realities
Charlotte BRIVES (CNRS UMR 5116, Bordeaux, France)
14:30 - 15:15 Phage therapy in the human clinic: the Georgian experience
Mzia KUTATELADZE (G. Eliava Institute of Bacteriophages, Microbiology and Virology, Georgie)
15:15 - 16:00 Phage therapy in the human clinic: the Belgian experience
Jean-Paul PIRNAY (Hôpital militaire Reine Astrid, Bruxelles, Belgique)
16:00 - 16:30 Coffee Break
16:30 - 17:15 Phage therapy in the human clinic: the French experience
Alexandre BLEIBTREU (APHP, Paris, France)
17:15 - 18:00 Which regulations for phage therapy in Europe for human/vet?
To be confirmed
18:00 - 18:45 Round table: Which models of development for phage therapy?
Alexandre BLEIBTREU, Frédéric LAURENT, Charlotte BRIVES, Jen-Paul PIRNAY, 
Mzia KUTATELADZE and Grégory RESCH
18:45 - 19:00 Presentation of the practical workshops
19:30 - 20:15 Cocktail
20:15 Dinner

Vendredi 24 Mai 2024 - Friday, May 24, 2024

06:30 - 08:30 Breakfast
SESSION IV BACTERIOPHAGES IN ECOSYSTEMS
08:30 - 09:15 Bacteriophages and microbiota
Luisa De SORDI (Sorbonne University, Paris, France)
09:15 - 10:00 Phages for biocontrol in agriculture
Clara TORRES-BARCELÓ (INRAE, Avignon, France)
10:00 - 10:30 Coffee Break
10:30 - 11:15 Phages in the agri-food industry
Claire LE HENAFF (University of Bordeaux, France)
11:15 - 12:00 Round Table: Which place for phages in the One health approach?
C. TORRES-BARCELÓ, C. LE HENAFF, F. LAURENT, R. FROISSART, L. DEBARBIEUX and C. BRIVES
12:00 - 14:00 Lunch
14:00 Departure

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