Atelier 278 - Epigénétique en santé : le point sur les maladies rares
Mardi 2 Avril 2024 ◘ Tuesday April, 2 2024 |
|
| 15:30 - 16:00 | Reception of participants |
| 16:00 - 16:15 | Welcome and presentation by the organizers |
| SESSION I | EPIGENETIC PROCESSES: STATE OF THE ART |
| 16:15 - 17:00 |
The Genetics and Epigenetics of Rett Syndrome |
| Adrian Bird (University of Edinburgh, Edimbourg, UK) | |
| 17:00 - 17:30 | Coffee break |
| 17:30 - 18:15 |
X chromosome inactivation, a paradigm for epigenetic regulations, in health and diseases |
| Claire Rougeulle (Epigénétique et Destin Cellulaire, CNRS, Paris Diderot, Paris, France) | |
| 18:15 - 19:00 |
Transposable elements as drivers of epigenetic regulation |
| Deborah Bourc’his (Curie Institute, Paris, France) | |
| 19:30 | Dinner |
Mercredi 3 Avril 2024 ◘ Wednesday April, 3 2024 |
|
| 06:30 - 08:30 | Breakfast |
| SESSION II | EPIGENETICS IN HEALTH |
| 08:30 - 09:15 | Energy metabolism and epigenetics: a focus on developmental origins of health and disease |
| Anne Gabory (INRA, Paris Saclay, France) | |
| 09:15 - 10:00 |
Epigenetic liquid biopsy |
| Yuval DOR (Institute for Biomedical Res, Jerusalem, Israel) | |
| 10:00 - 10:30 | Coffee break |
| 10:30 - 11:15 |
Epigenomics of nerve sheath sarcomas associated with neurofibromatosis type 1 |
| Eric Pasmant (Institut Cochin, Paris, France) | |
| 11:15 - 12:00 |
The breaking and reshaping of regulatory landscapes in development and disease |
| Michael Robson (Max Planck Institute for Molecular Genetics, Berlin, Allemagne) | |
| 12:00 - 14:00 | Lunch |
| SESSION III | EPIGENETICS AND RARE DISEASES |
| 14:00 - 14:45 | Titre de la présentation |
| Michael S. Kobor (BC Children’s Hospital, Vancouver, Canada) | |
| 14:45 - 15:30 |
Epigenetic strategies for the diagnosis of rare diseases |
| Maria J. Barrero (Spanish National Institute of Health Carlos III, Madrid, Spain) | |
| 15:30 - 16:00 | Coffee Break |
| 16:00 - 16:45 |
Addressing Challenges and Limitations in Epigsignature for Rare Diseases (computational and statistical considerations) |
| Matthieu DeFrance (Interuniversity Institute of Bioinformatics in Brussels, Belgium) | |
| 16:45 - 17:30 |
Genome editing for correction of pathogenic variants in a rare chromatin-related disease |
| Maria Matarazzo (Institute of Genetics and Biophysics-CNR, Naples, Italy) | |
| 17:30 - 18:15 |
Genome dysfunctions captured by chromatin solubility |
| Chiara Lanzuolo (San Raffaele, Milan, Italy) | |
| 19:30 - 20:15 | Cocktail |
| 20:15 | Dinner |
Jeudi 4 Avril 2024 ◘ Thursday April, 4 2024 |
|
| 06:30 - 08:30 | Breakfast |
| SESSION IV | EPIDRUGS ET DRUG DESIGN |
| 08:30 - 09:15 |
Druggable epigenome in cancer: challenges and limitations |
| Maria Berdasco (Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain) | |
| 09:15 - 10:00 |
AntiDOTes for diseases: Chemistry and Biology match together to tackle Epigenetics |
| Paola Arimondo (Institut Pasteur, Paris, France) | |
| 10:00 - 10:30 | Coffee Break |
| 10:30 - 11:15 | Decoding the unseen: Using protein interaction to guide AI-designed peptide epidrugs without structural blueprints |
| Kyle Biggar (Carleton University, Ottawa, Canada) | |
| 11:15 - 12:00 | Closing remarks and round Table |
| 12:00 - 14:00 | Lunch |
| 14:00 | Departure |